Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783749 | 0.84 | NR4A1 (0.50) | ALOX5ALDH1A1PTPN1MAOAMAOB | |
| SCHEMBL22146818 | 0.82 | ALOX5 (0.52) | MAPTNPC1KMT2AALOX5TSHR | |
| SCHEMBL22645255 | 0.81 | MAPT (0.53) | MAPTNPC1KMT2AAKR1C3TSHR | |
| SCHEMBL516118 | 0.80 | ALOX5 (0.52) | MAPTALOX5ALDH1A1GAAHDAC1 | |
| SCHEMBL371291 | 0.80 | GABRP (0.46) | MAPTNPC1KMT2AALOX5PTPN1 | |
| SCHEMBL17036994 | 0.80 | HDAC1 (0.43) | MAPTNPC1KMT2AALOX5ALDH1A1 | |
| SCHEMBL7815593 | 0.80 | NPSR1 (0.47) | KMT2AALOX5ALDH1A1GAAHDAC1 | |
| SCHEMBL4586057 | 0.79 | ALOX5 (0.48) | MAPTNPC1KMT2AALOX5ALDH1A1 | |
| SCHEMBL14825579 | 0.79 | ALOX5 (0.48) | MAPTNPC1KMT2AALOX5ALDH1A1 | |
| SCHEMBL28084237 | 0.79 | ALDH1A1 (0.59) | MAPTNPC1KMT2AALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836723-B2 | Method for synthesizing sodium 2,2,6,6-tetramethylpiperidides | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |