Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22194257 | 0.86 | HRH4 (0.35) | ALDH1A1HSD17B10CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL3365138 | 0.72 | HTR2C (0.47) | ALDH1A1HRH3 | |
| SCHEMBL14892841 | 0.69 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL4025127 | 0.69 | PIK3CA (0.40) | CYP1A2CYP2C9 | |
| SCHEMBL30720610 | 0.69 | CHRNA4 (0.35) | CHRNA4 | |
| SCHEMBL5313919 | 0.69 | CHKA (0.37) | ALDH1A1HSD17B10CYP1A2TSHRHPGD | |
| SCHEMBL21667712 | 0.68 | CYP2C9 (0.54) | ALDH1A1HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29619517 | 0.68 | MAP3K12 (0.34) | — | |
| SCHEMBL30818712 | 0.65 | HRH3 (0.49) | ALDH1A1HSD17B10CYP1A2TSHRHRH3 | |
| SCHEMBL30818660 | 0.65 | LRRK2 (0.45) | ALDH1A1HSD17B10CYP3A4CYP1A2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040972-B2 | Autotaxin inhibitors and uses thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200354357-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040972-B2 | Autotaxin inhibitors and uses thereof | ENPP2, SERPINB1, RNASE1 | ALDH1A1 4716/4885HSD17B10 2721/4885CYP3A4 4633/4885 |
| US-20200354357-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SERPINB1, RNASE1 | ALDH1A1 4716/4885HSD17B10 2721/4885CYP3A4 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.