Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061684 | 0.79 | GABRA1 (0.42) | CYP1A2CYP2A6CA2KIF11PSMB8 | |
| SCHEMBL22645752 | 0.78 | CA2 (0.33) | CA2KIF11PSMB8PSMB5 | |
| SCHEMBL22645755 | 0.76 | TP53 (0.35) | PSMB8PSMB5 | |
| SCHEMBL22645749 | 0.76 | CA2 (0.36) | CA2KIF11ALDH1A1 | |
| SCHEMBL2095750 | 0.75 | CYP1A2 (0.42) | CYP1A2CYP2A6AHRNR4A2PSMB8 | |
| SCHEMBL22645753 | 0.73 | TP53 (0.31) | — | |
| SCHEMBL25027565 | 0.71 | CYP1A2 (0.42) | CYP1A2CYP2A6AHRNR4A2PSMB8 | |
| SCHEMBL2091325 | 0.71 | CYP1A2 (0.42) | CYP1A2CYP2A6AHRNR4A2PSMB8 | |
| SCHEMBL11538924 | 0.69 | CES1 (0.42) | CYP1A2CYP2A6AHRNR4A2ALDH1A1 | |
| SCHEMBL2607820 | 0.68 | MAOB (0.40) | CA2KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858951-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2024-01-02 | — | — | US | disclosed |
| US-11858951-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2024-01-02 | — | — | US | disclosed |
| US-20220153761-A1 | Boronic Acid Derivatives | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
| US-11274109-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2022-03-15 | — | — | US | disclosed |
| US-20200354382-A1 | Boronic Acid Derivatives | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153761-A1 | Boronic Acid Derivatives | PSMB7, PSMA7, BRD7 | CYP1A2 4777/4885CYP2A6 3357/4885AHR 1695/4885 |
| US-11274109-B2 | Boronic acid derivatives | PSMB7, PSMA7, BRD7 | CYP1A2 4786/4885CYP2A6 3365/4885AHR 1708/4885 |
| US-11858951-B2 | Boronic acid derivatives | PSMB7, PSMA7, BRD7 | CYP1A2 4777/4885CYP2A6 3357/4885AHR 1695/4885 |
| US-20200354382-A1 | Boronic Acid Derivatives | PSMB7, PSMA7, BRD7 | CYP1A2 4786/4885CYP2A6 3365/4885AHR 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.