Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 5/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | PPP5C | P53041 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10214195 | 1.00 | GABRR1 (0.39) | GABRR1GRM2GABRR2PPP5CSLC1A2 | |
| SCHEMBL22656590 | 0.84 | GABRR1 (0.50) | GABRR1GRM2GABRR2SLC1A2LMNA | |
| SCHEMBL27224128 | 0.84 | GABRR1 (0.50) | GABRR1GRM2GABRR2SLC1A2LMNA | |
| SCHEMBL109579 | 0.84 | GABRR1 (0.50) | GABRR1GRM2GABRR2SLC1A2LMNA | |
| SCHEMBL14338304 | 0.84 | SLC1A2 (0.38) | GABRR1GRM2GABRR2SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL28992700 | 0.82 | GABRR1 (0.48) | GABRR1GRM2GABRR2SLC1A2LMNA | |
| SCHEMBL13533362 | 0.79 | EPHX1 (0.45) | — | |
| SCHEMBL13179065 | 0.77 | CHRNB2 (0.39) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL22617335 | 0.74 | CHRNB2 (0.41) | GABRR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15440659 | 0.74 | CHRNB2 (0.41) | GABRR1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274109-B2 | Boronic acid derivatives | MERCK PATENT GMBH (DE) | 2022-03-15 | — | — | US | disclosed |
| US-20200354382-A1 | Boronic Acid Derivatives | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274109-B2 | Boronic acid derivatives | PSMB7, PSMA7, BRD7 | GABRR1 1124/4885GRM2 3441/4885GABRR2 1377/4885 |
| US-20200354382-A1 | Boronic Acid Derivatives | PSMB7, PSMA7, BRD7 | GABRR1 1124/4885GRM2 3441/4885GABRR2 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.