Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.38 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSH | P09668 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525065 | 0.74 | ECE1 (0.45) | DPP7DPP9DPP8DPP4GRIK1 | |
| SCHEMBL11523628 | 0.72 | PLA2G2C (0.39) | CTSKHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL20183116 | 0.72 | TAS1R3 (0.30) | TAS1R3TAS1R1 | |
| SCHEMBL19090986 | 0.71 | CA12 (0.39) | DPP7DPP9DPP8DPP4CTSC | |
| SCHEMBL11525696 | 0.71 | CYP2C9 (0.41) | CTSKHDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL15866437 | 0.70 | PAX8 (0.35) | DPP9DPP8DPP4 | |
| SCHEMBL10888528 | 0.70 | DPP4 (0.44) | DPP7DPP9DPP8DPP4SLC15A1 | |
| SCHEMBL10891150 | 0.70 | DPP4 (0.44) | DPP7DPP9DPP8DPP4SLC15A1 | |
| SCHEMBL14899283 | 0.70 | CAPN1 (0.45) | DPP9DPP8DPP4CTSBCTSK | |
| SCHEMBL3678079 | 0.70 | CTSK (0.48) | DPP7DPP9DPP8DPP4CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225245-A1 | VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF | IPROTEOS, S.L. (ES) | 2020-11-12 | — | — | WO | disclosed |