SCHEMBL11525696

SCHEMBL11525696

C=CC(CCC)NC(=O)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.41
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
FAAH O00519 1/20 0.34
ITGB3 P05106 3/20 0.34
ITGA2B P08514 3/20 0.34
TSHR P16473 4/20 0.33
CTSK P43235 2/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525715 0.83 CYP2C9 (0.43) CYP2C9FAAHITGB3ITGA2BTSHR
SCHEMBL11523628 0.82 PLA2G2C (0.39) CYP2C9TAS1R3TAS1R1FAAHTSHR
SCHEMBL20183116 0.73 TAS1R3 (0.30) TAS1R3TAS1R1
SCHEMBL23009079 0.73 CTSK (0.51) CTSK
SCHEMBL22161279 0.73 CASP2 (0.37) FAAHITGB3ITGA2BHDAC8HDAC6
SCHEMBL726297 0.72
SCHEMBL11564239 0.72
SCHEMBL22648329 0.71 DPP7 (0.38) TAS1R3TAS1R1CTSKHDAC7HDAC8
SCHEMBL23009217 0.71 L3MBTL1 (0.33) TAS1R3TAS1R1CTSK
SCHEMBL7796596 0.71 NPC1 (0.46) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179292-A Light-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed