Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361717 | 0.84 | ACHE (0.35) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL31361696 | 0.84 | ACHE (0.35) | ADORA2AADORA1KMT2ARAB9ANPC1 | |
| SCHEMBL12460196 | 0.84 | ACHE (0.38) | HPGDRAB9AKDM4ENPC1ACHE | |
| SCHEMBL16532142 | 0.81 | FPR2 (0.41) | KMT2AHPGDRAB9AKDM4ENPC1 | |
| SCHEMBL29427432 | 0.81 | KDM4E (0.43) | KMT2ARAB9AKDM4ENPC1LMNA | |
| SCHEMBL19020973 | 0.78 | SYK (0.39) | ADORA2AADORA1KMT2AACHEMEN1 | |
| SCHEMBL15650220 | 0.78 | ALDH1A1 (0.40) | ADORA2AADORA1KDM4EACHEALDH1A1 | |
| SCHEMBL15564730 | 0.77 | HPGD (0.42) | KMT2AHPGDLMNACYP1A2CYP3A4 | |
| SCHEMBL26078457 | 0.77 | SMN1; SMN2 (0.53) | KMT2ARAB9ANPC1LMNACYP1A2 | |
| SCHEMBL17076750 | 0.74 | CCNC (0.46) | ADORA2AADORA1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312589-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. | 2023-10-05 | — | — | US | disclosed |
| WO-2021026465-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2020227563-A1 | JAK INHIBITORS | VIMALAN BIOSCIENCES, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312589-A1 | JAK INHIBITORS | JAK2, JAK1, JAK3 | ADORA3 4117/4885ADORA2A 3579/4885ADORA1 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.