Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361717 | 1.00 | ACHE (0.35) | ACHERECQLNPC1RAB9ARXFP1 | |
| SCHEMBL16051035 | 1.00 | ACHE (0.35) | ACHERECQLNPC1RAB9ARXFP1 | |
| SCHEMBL22648680 | 0.84 | ADORA3 (0.39) | ACHENPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL25027007 | 0.81 | ALDH1A1 (0.37) | ACHERECQLNPC1RAB9ARXFP1 | |
| SCHEMBL19020973 | 0.81 | SYK (0.39) | ACHESMN1; SMN2KMT2AMEN1ADORA2A | |
| SCHEMBL15650220 | 0.81 | ALDH1A1 (0.40) | ACHEADORA2AADORA1 | |
| SCHEMBL16584237 | 0.80 | KDM4E (0.38) | ACHERECQLNPC1RAB9AKMT2A | |
| SCHEMBL1581745 | 0.80 | ELANE (0.36) | ACHERECQLNPC1RAB9ARXFP1 | |
| SCHEMBL19010789 | 0.80 | PLK4 (0.41) | ACHENPC1RAB9ARXFP1SMN1; SMN2 | |
| SCHEMBL12993521 | 0.80 | ELANE (0.36) | ACHERECQLNPC1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |