Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886067 | 0.77 | CYP1A2 (0.38) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2263612 | 0.76 | MEN1 (0.34) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2263208 | 0.73 | EPHX1 (0.34) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2260665 | 0.70 | CA1 (0.48) | — | |
| SCHEMBL7539963 | 0.69 | CHRNB2 (0.33) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL2261893 | 0.69 | CA1 (0.32) | — | |
| SCHEMBL24404223 | 0.68 | — | — | |
| SCHEMBL30143782 | 0.68 | TSHR (0.59) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL29222354 | 0.67 | SIGMAR1 (0.50) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL23121455 | 0.67 | SIGMAR1 (0.50) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247467-A1 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | FIRMENICH SA (CH) | 2010-09-30 | — | — | US | claimed |
| CN-101848889-A | Alpha-substituted cyclopentanecarbonitriles or cyclohexanecarbonitriles and their use in perfumery | FIRMENICH & CIE | 2010-09-29 | — | — | CN | claimed |
| EP-2217563-A2 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | Firmenich S.A. (CH) | 2010-08-18 | — | — | EP | claimed |
| WO-2009060378-A2 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | FIRMENICH SA (CH) | 2009-05-14 | — | — | WO | claimed |
| CN-101848889-B | Alpha-substituted cyclopentanecarbonitriles or cyclohexanecarbonitriles and their use in perfumery | FIRMENICH & CIE | 2013-07-17 | — | — | CN | disclosed |
| EP-2217563-B1 | Alpha-substituted cyclopentanecarbonitriles or cyclohexanecarbonitriles and their use in perfumery | FIRMENICH & CIE (CH) | 2013-01-30 | — | — | EP | disclosed |
| US-8003084-B2 | α-substituted cyclopentanecarbonitriles or cyclohexanecarbonitriles and their use in perfumery | FIRMENICH SA (CH) | 2011-08-23 | — | — | US | disclosed |
| US-20100247467-A1 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | FIRMENICH SA (CH) | 2010-09-30 | — | — | US | disclosed |
| CN-101848889-A | Alpha-substituted cyclopentanecarbonitriles or cyclohexanecarbonitriles and their use in perfumery | FIRMENICH & CIE | 2010-09-29 | — | — | CN | disclosed |
| EP-2217563-A2 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | Firmenich S.A. (CH) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009060378-A2 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | FIRMENICH SA (CH) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247467-A1 | ALPHA-SUBSTITUTED CYCLOPENTANECARBONITRILES OR CYCLOHEXANECARBONITRILES AND THEIR USE IN PERFUMERY | PNN, FASN, CYP8B1 | CHRNB2 657/4885CHRNA7 687/4885CHRNA4 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.