Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515063 | 0.83 | CYP1A2 (0.37) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL24311127 | 0.77 | SIGMAR1 (0.53) | TSHR | |
| SCHEMBL8651869 | 0.76 | CHRNB2 (0.31) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL8370406 | 0.74 | CHRNB2 (0.30) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL29336691 | 0.74 | SIGMAR1 (0.50) | — | |
| SCHEMBL2996217 | 0.74 | SIGMAR1 (0.45) | — | |
| SCHEMBL9801592 | 0.74 | SIGMAR1 (0.54) | TSHR | |
| SCHEMBL28815681 | 0.74 | SIGMAR1 (0.54) | TSHR | |
| SCHEMBL1162323 | 0.74 | SIGMAR1 (0.54) | TSHR | |
| SCHEMBL11133777 | 0.73 | CYP1A2 (0.41) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020197732-A1 | Method and apparatus for combinatorial screening of polymer compositions | GENERAL ELECTRIC COMPANY | 2002-12-26 | — | — | US | disclosed |
| US-4399251-A | HEAT RESISTANCE; NONHYDROLYZING; INJECTION MOLDING | GENERAL ELECTRIC COMPANY (US) | 1983-08-16 | — | — | US | disclosed |