Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22636372 | 0.81 | PLK1 (0.53) | PPARGPPARA | |
| SCHEMBL22650327 | 0.77 | METAP2 (0.50) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL4578324 | 0.76 | HNF4A (0.54) | ALDH1A1HNF4AAKR1C3AKR1C2FFAR1 | |
| SCHEMBL14383904 | 0.74 | GAA (0.45) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL3825804 | 0.74 | KDM4E (0.69) | MEN1KMT2AALDH1A1L3MBTL1PPARG | |
| SCHEMBL4606051 | 0.71 | HNF4A (0.54) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL14254798 | 0.70 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL4839372 | 0.69 | MEN1 (0.68) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL1743408 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL7230992 | 0.67 | KDM4E (0.51) | MEN1KMT2AGAAKDM4EMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225330-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2020-11-12 | — | — | WO | disclosed |