SCHEMBL22650223

SCHEMBL22650223

Cc1nc(-c2cccnc2)c(I)s1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 11/20 0.49
CYP3A4 P08684 9/20 0.45
CYP1A2 P05177 3/20 0.45
NPY5R Q15761 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP2E1 P05181 6/20 0.45
CYP2C9 P11712 6/20 0.45
CYP2B6 P20813 6/20 0.45
CYP2C19 P33261 6/20 0.44
LMNA P02545 1/20 0.44
CYP2D6 P10635 4/20 0.42
GRM5 P41594 1/20 0.41
MAP2K4 P45985 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CDC7 O00311 1/20 0.40
DBF4 Q9UBU7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8472476 0.83 CYP2A6 (0.51) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1
SCHEMBL22650293 0.80 NTRK1 (0.51) CYP1A2ALDH1A1CYP2C19CYP2D6RAB9A
SCHEMBL31469332 0.80 CYP2A6 (0.49) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1
SCHEMBL9727832 0.80 CYP2A6 (0.49) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1
SCHEMBL22650224 0.79 ALDH1A1 (0.39) CYP3A4CYP1A2ALDH1A1CYP2C9CYP2C19
SCHEMBL13494032 0.75 GPR35 (0.54) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1
SCHEMBL17590206 0.73 CYP3A4 (0.58) CYP2A6CYP3A4CYP1A2ALDH1A1CYP2E1
SCHEMBL15791180 0.72 CYP2A6 (0.52) CYP2A6CYP3A4CYP1A2ALDH1A1CYP2E1
SCHEMBL13910994 0.71 CYP2A6 (0.70) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1
SCHEMBL31469304 0.71 CYP2A6 (0.40) CYP2A6CYP3A4CYP1A2NPY5RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT FUJIFILM CORPORATION (JP) 2020-11-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354576-A1 DYEING COMPOSITION, DYED PRODUCT, AND AZO COLORING AGENT CYP1B1, CYP1A1, NAT1 CYP2A6 281/4885CYP3A4 176/4885CYP1A2 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.