Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472476 | 0.83 | CYP2A6 (0.51) | CYP2A6CYP3A4CYP1A2ALDH1A1NPY5R | |
| SCHEMBL17592709 | 0.80 | NTRK1 (0.51) | CYP1A2ALDH1A1CYP2C19CYP2D6SMN1; SMN2 | |
| SCHEMBL22650223 | 0.80 | CYP2A6 (0.49) | CYP2A6CYP3A4CYP1A2ALDH1A1NPY5R | |
| SCHEMBL9727832 | 0.80 | CYP2A6 (0.49) | CYP2A6CYP3A4CYP1A2ALDH1A1NPY5R | |
| SCHEMBL5516349 | 0.76 | CYP2A6 (0.49) | CYP2A6CYP3A4CYP1A2ALDH1A1CYP2E1 | |
| SCHEMBL5519397 | 0.76 | CYP2A6 (0.41) | CYP2A6CYP3A4CYP1A2ALDH1A1CYP2E1 | |
| SCHEMBL13494032 | 0.75 | GPR35 (0.54) | CYP2A6CYP3A4CYP1A2ALDH1A1NPY5R | |
| SCHEMBL1679638 | 0.73 | CYP3A4 (0.58) | CYP2A6CYP3A4CYP1A2ALDH1A1CYP2E1 | |
| SCHEMBL17188772 | 0.73 | PTGS2 (0.53) | ALDH1A1NFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL13910994 | 0.71 | CYP2A6 (0.70) | CYP2A6CYP3A4CYP1A2ALDH1A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |