Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650436 | 0.81 | RPS6KA5 (0.34) | SCN5ARPS6KA5SMN1; SMN2 | |
| SCHEMBL22650740 | 0.81 | RPS6KA5 (0.32) | RPS6KA5SMN1; SMN2JAK2 | |
| SCHEMBL22650369 | 0.78 | SCN5A (0.38) | SCN5ASMN1; SMN2JAK2 | |
| SCHEMBL22650908 | 0.77 | CAMKK1 (0.38) | SCN5ARPS6KA5 | |
| SCHEMBL22650437 | 0.74 | SCN5A (0.42) | SCN5ARPS6KA5SMN1; SMN2 | |
| SCHEMBL22650698 | 0.71 | MAPK14 (0.35) | — | |
| SCHEMBL20356475 | 0.70 | RPS6KA5 (0.35) | RPS6KA5SMN1; SMN2 | |
| SCHEMBL19966561 | 0.68 | KMO (0.38) | SMN1; SMN2 | |
| SCHEMBL29520298 | 0.68 | NPC1 (0.39) | RPS6KA5SMN1; SMN2 | |
| SCHEMBL31489405 | 0.68 | PDE10A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |