Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | SERPINA2 | P20848 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650468 | 0.75 | CDK6 (0.41) | PIK3CDCDK2 | |
| SCHEMBL22650436 | 0.74 | RPS6KA5 (0.34) | — | |
| SCHEMBL22650704 | 0.73 | PIK3CA (0.36) | MAPK14PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL22650908 | 0.72 | CAMKK1 (0.38) | PIK3CAMAPK1CDK2 | |
| SCHEMBL22650740 | 0.71 | RPS6KA5 (0.32) | PIK3CG | |
| SCHEMBL22650356 | 0.71 | SCN5A (0.39) | — | |
| SCHEMBL22650437 | 0.69 | SCN5A (0.42) | PIK3CD | |
| SCHEMBL22650697 | 0.66 | MAPK1 (0.41) | MAPK1HTR1DCDC7CDK2 | |
| SCHEMBL3313922 | 0.65 | DYRK1A (0.47) | PIK3CBCDK2 | |
| SCHEMBL31488065 | 0.64 | PDK4 (0.44) | EEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |