Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650368 | 0.81 | ALOX5AP (0.37) | DDB1CRBNL3MBTL3AKR1C3 | |
| SCHEMBL29462389 | 0.81 | ALOX5AP (0.37) | DDB1CRBNL3MBTL3AKR1C3 | |
| SCHEMBL22650563 | 0.80 | BPTF (0.41) | DDB1CRBNL3MBTL3SLC6A2SLC6A4 | |
| SCHEMBL31347314 | 0.80 | BPTF (0.41) | DDB1CRBNL3MBTL3SLC6A2SLC6A4 | |
| SCHEMBL22650567 | 0.79 | LMNA (0.41) | ALDH1A1POLBHTTHSD17B10TSHR | |
| SCHEMBL1409679 | 0.75 | MAPT (0.53) | L3MBTL3KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL1750723 | 0.74 | HDAC8 (0.43) | DDB1CRBNCYP19A1KMT2AKDM4E | |
| SCHEMBL188110 | 0.72 | MCHR1 (0.48) | KMT2AKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL188535 | 0.72 | MCHR1 (0.48) | KMT2AKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL188111 | 0.72 | MCHR1 (0.48) | KMT2AKDM4EMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |