Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347314 | 1.00 | BPTF (0.41) | BPTFTSHRFPR1FPR2SLC6A2 | |
| SCHEMBL22650567 | 0.83 | LMNA (0.41) | TSHRPOLBHSD11B1HTR2C | |
| SCHEMBL22650565 | 0.80 | DDB1 (0.38) | TSHRSLC6A2SLC6A4POLBL3MBTL3 | |
| SCHEMBL20374556 | 0.79 | NPY5R (0.41) | FPR1FPR2HSD11B1L3MBTL3NPY5R | |
| SCHEMBL22650572 | 0.77 | CCR5 (0.38) | BPTFTSHRDPP4 | |
| SCHEMBL31084534 | 0.77 | FPR1 (0.44) | FPR1FPR2NPY5R | |
| SCHEMBL4259168 | 0.77 | FPR1 (0.44) | FPR1FPR2NPY5R | |
| SCHEMBL4263614 | 0.77 | FPR1 (0.44) | FPR1FPR2NPY5R | |
| SCHEMBL22650368 | 0.75 | ALOX5AP (0.37) | L3MBTL3ALOX5APFEN1DDB1CRBN | |
| SCHEMBL29462389 | 0.75 | ALOX5AP (0.37) | L3MBTL3ALOX5APFEN1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |