Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | GCKR | Q14397 | 6/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650390 | 0.92 | ROCK2 (0.38) | CHRNB2CHRNA4GCKRCPB1ROCK2 | |
| SCHEMBL22650413 | 0.81 | DDB1 (0.38) | AKR1C3ROCK2FPR2FPR1 | |
| SCHEMBL22650346 | 0.81 | ROCK2 (0.37) | GCKRGCKROCK2CDK4PIK3CA | |
| SCHEMBL18291533 | 0.80 | PIM1 (0.41) | AKR1C3CHRNB2CHRNA4GCKRCPB1 | |
| SCHEMBL2301307 | 0.74 | CDK4 (0.44) | CHRNB2CHRNA4CPB1CDK4 | |
| SCHEMBL22650368 | 0.73 | ALOX5AP (0.37) | AKR1C3CHRNB2CHRNA4GCKRPIK3CA | |
| SCHEMBL29462389 | 0.73 | ALOX5AP (0.37) | AKR1C3CHRNB2CHRNA4GCKRPIK3CA | |
| SCHEMBL24747195 | 0.72 | MCHR1 (0.43) | CHRNB2CHRNA4ROCK2CDK4PIK3CA | |
| SCHEMBL29112389 | 0.72 | MCHR1 (0.43) | CHRNB2CHRNA4ROCK2CDK4PIK3CA | |
| SCHEMBL29112270 | 0.72 | MCHR1 (0.43) | CHRNB2CHRNA4ROCK2CDK4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |