Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750723 | 0.90 | HDAC8 (0.43) | DDB1CRBNHDAC8HDAC6KDM4E | |
| SCHEMBL22650588 | 0.81 | AKR1C3 (0.36) | FPR1FPR2AKR1C3ROCK2 | |
| SCHEMBL5958870 | 0.79 | HDAC8 (0.37) | DDB1CRBNHDAC8HDAC6KDM4E | |
| SCHEMBL22650381 | 0.78 | ROCK2 (0.38) | HDAC8HDAC6FPR1FPR2GFER | |
| SCHEMBL22650390 | 0.72 | ROCK2 (0.38) | HDAC8HDAC6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22650565 | 0.69 | DDB1 (0.38) | DDB1CRBNKDM4EMAPTALDH1A1 | |
| SCHEMBL4712503 | 0.69 | FPR2 (0.49) | FPR1FPR2 | |
| SCHEMBL4847013 | 0.68 | DDB1 (0.43) | DDB1CRBNHDAC8HDAC6KDM4E | |
| SCHEMBL2698184 | 0.67 | HDAC8 (0.46) | DDB1CRBNHDAC8HDAC6KDM4E | |
| SCHEMBL3440110 | 0.67 | MAPT (0.53) | KDM4EMAPTALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |