Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 18/20 | 0.41 |
| ▸ | CDK4 | P11802 | 13/20 | 0.41 |
| ▸ | CCND3 | P30281 | 9/20 | 0.41 |
| ▸ | CCND1 | P24385 | 8/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.41 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | CDK9 | P50750 | 5/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.41 |
| ▸ | CDK7 | P50613 | 3/20 | 0.41 |
| ▸ | CCNH | P51946 | 3/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650591 | 0.83 | CDK6 (0.48) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL22650471 | 0.83 | CDK4 (0.46) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL22650467 | 0.83 | CDK4 (0.49) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL22650698 | 0.75 | MAPK14 (0.35) | CDK2PIK3CD | |
| SCHEMBL22650401 | 0.74 | NTRK1 (0.46) | CDK6CDK4CCNA2CDK2JAK2 | |
| SCHEMBL22650487 | 0.73 | CDK4 (0.42) | CDK6CDK4CCNA2CDK2CDK9 | |
| SCHEMBL22650928 | 0.72 | CDK6 (0.50) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL22650601 | 0.72 | CDK6 (0.48) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL22650486 | 0.72 | CDK6 (0.54) | CDK6CDK4CCND3CCND1CCNA2 | |
| SCHEMBL29491147 | 0.72 | CDK6 (0.54) | CDK6CDK4CCND3CCND1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |