Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792958 | 0.83 | MAPT (0.34) | PDE7AHTTALDH1A1MAPTTDP1 | |
| SCHEMBL3632961 | 0.70 | ESR2 (0.40) | PDE7AALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL16674748 | 0.70 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1POLBCYP2C19 | |
| SCHEMBL13155557 | 0.70 | FFAR2 (0.30) | — | |
| SCHEMBL31549306 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1POLBMAPK1 | |
| SCHEMBL6611730 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTTDP1POLBCYP1A2 | |
| SCHEMBL10747144 | 0.69 | PDE7A (0.33) | PDE7AHTTALDH1A1MAPTTDP1 | |
| SCHEMBL4592291 | 0.68 | MEN1 (0.46) | HTTALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL4648233 | 0.67 | — | — | |
| SCHEMBL10102505 | 0.67 | PDE7A (0.38) | PDE7AHTTALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395573-B | Process for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2014-05-07 | — | — | CN | disclosed |
| CN-103467443-A | Process for production of 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2013-12-25 | — | — | CN | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367846-B2 | Method of producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO, INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| CN-102395573-A | Process for producing 2-alkyl-3-aminothiophene derivative | MITSUI CHEMICALS AGRO INC | 2012-03-28 | — | — | CN | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267963-A1 | METHOD OF PRODUCING 2-ALKYL-3-AMINOTHIOPHENE DERIVATIVE | CBR3, CYP2E1, SULT2A1 | PDE7A 4634/4885HTT 2620/4885ALDH1A1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.