Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644962 | 0.90 | HDAC1 (0.42) | HDAC6HDAC1 | |
| SCHEMBL15469243 | 0.77 | HSD17B10 (0.34) | GABRA5GABRB2HSD17B10 | |
| SCHEMBL16095853 | 0.72 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL16644964 | 0.71 | HDAC6 (0.37) | HDAC6 | |
| SCHEMBL20751486 | 0.71 | RXRA (0.34) | — | |
| SCHEMBL15469205 | 0.71 | CYP1A2 (0.37) | HDAC6HDAC1HSD17B10 | |
| SCHEMBL20536570 | 0.71 | PGK1 (0.39) | — | |
| SCHEMBL20536064 | 0.70 | PGK1 (0.38) | HDAC6HDAC1 | |
| SCHEMBL22652851 | 0.70 | LTB4R (0.44) | HDAC6HDAC1 | |
| SCHEMBL15417769 | 0.69 | SLC6A3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227105-A1 | ANTI-BCMA ANTIBODY CONJUGATES | SUTRO BIOPHARMA, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| EP-3055298-B1 | MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-2890402-B1 | MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP | SUTRO BIOPHARMA INC (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2859017-B1 | ANTIBODIES COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2019-02-20 | — | — | EP | disclosed |