Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22653502 | 0.75 | MAPK8 (0.39) | HPGDMCL1MAPK8MAPK10POLB | |
| SCHEMBL10556645 | 0.73 | MAPT (0.41) | HPGDPOLBL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL22069448 | 0.72 | MAOB (0.40) | HPGDMCL1MAPK8MAPK10THRB | |
| SCHEMBL6734372 | 0.71 | PPARA (0.32) | POLBL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL22653500 | 0.71 | KDM4E (0.48) | POLBL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22653503 | 0.69 | MAPK8 (0.39) | HPGDMCL1MAPK8MAPK10THRB | |
| SCHEMBL22089886 | 0.68 | THRB (0.38) | HPGDMAPK8MAPK10POLBL3MBTL1 | |
| SCHEMBL22653507 | 0.68 | LMNA (0.37) | HPGDMCL1MAPK8MAPK10L3MBTL1 | |
| SCHEMBL22685080 | 0.67 | THRB (0.35) | HPGDMAPK8MAPK10ATMBLM | |
| SCHEMBL22653505 | 0.65 | LMNA (0.37) | HPGDMAPK8MAPK10THRBEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738959-A1 | PREPARATION OF 6-PHENOXY-2-(HALOALKYL)-3-ACYLPYRIDINES AND INTERMEDIATES THEREFOR | Bayer AG (DE) | 2020-11-18 | — | — | EP | disclosed |