SCHEMBL22654024

SCHEMBL22654024

O=C[C@H](Br)N1CC([N+](=O)[O-])([N+](=O)[O-])C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29265156 0.67 CRHBP (0.34)
SCHEMBL23441696 0.67
SCHEMBL11230782 0.67 GAA (0.36)
SCHEMBL17484747 0.64 ALDH1A1 (0.32)
SCHEMBL9921596 0.61 GAA (0.38)
SCHEMBL436830 0.61 GAA (0.33)
SCHEMBL7248680 0.61 GAA (0.33)
SCHEMBL9918125 0.60 CYP2D6 (0.32)
SCHEMBL11230841 0.58 GAA (0.35)
SCHEMBL11044912 0.58 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4072617-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EpicentRx, Inc. (US) 2022-10-19 EP claimed
WO-2021119433-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EPICENTRX, INC. (US) 2021-06-17 WO claimed
EP-3801678-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EpicentRx, Inc. (US) 2021-04-14 EP claimed
WO-2023215229-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PULMONARY HYPERTENSION EPICENTRX, INC. (US) 2023-11-09 WO disclosed
WO-2023077016-A1 TARGETING NEURONAL SIRPΑ FOR TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS BAYLOR COLLEGE OF MEDICINE (US) 2023-05-04 WO disclosed
EP-4072617-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EpicentRx, Inc. (US) 2022-10-19 EP disclosed
WO-2021119433-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EPICENTRX, INC. (US) 2021-06-17 WO disclosed
EP-3801678-A1 MEDICATION INFUSION DEVICES, SYSTEMS, AND METHODS EpicentRx, Inc. (US) 2021-04-14 EP disclosed
EP-3737372-A2 METHODS AND COMPOSITIONS UTILIZING RRX-001 FOR RADIOPROTECTION EpicentRx, Inc. (US) 2020-11-18 EP disclosed