SCHEMBL22654072

SCHEMBL22654072

C=Cc1c(Cl)ccc(F)c1-c1c(C(C)(C)C(=O)O)c(C)nn(C)c1=O.Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2Br)c1C(C)(C)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444578 0.94 AKR1C3 (0.32) KMT2A
SCHEMBL28443368 0.92 KMT2A (0.34) MEN1KMT2A
SCHEMBL28924726 0.81 GPR183 (0.34) MEN1KMT2A
SCHEMBL22654074 0.79
SCHEMBL28946345 0.77 P4HB (0.32)
SCHEMBL28440263 0.77 MGLL (0.31)
SCHEMBL28445791 0.76 CNR1 (0.32)
SCHEMBL29263859 0.76 LMNA (0.31)
SCHEMBL28444233 0.74 GRM4 (0.36)
SCHEMBL22031802 0.73 KMT2A (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3737667-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2020-11-18 EP disclosed