SCHEMBL28440263

SCHEMBL28440263

Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2/C=C/c2ccc(C3CC3)cc2)c1C(C)(C)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CCR2 P41597 3/20 0.31
SRD5A1 P18405 1/20 0.30
SRD5A2 P31213 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28924726 0.90 GPR183 (0.34) CYP3A4CYP2C9
SCHEMBL28946345 0.86 P4HB (0.32)
SCHEMBL28445791 0.83 CNR1 (0.32) CYP3A4CYP2C9
SCHEMBL29216938 0.82 SMN1; SMN2 (0.35)
SCHEMBL28728533 0.81
SCHEMBL29216939 0.81 CCR2 (0.31) MGLLCCR2
SCHEMBL28444578 0.81 AKR1C3 (0.32)
SCHEMBL29263843 0.81 GPR183 (0.36)
SCHEMBL22654069 0.80 FPR2 (0.31) MGLL
SCHEMBL29216941 0.79 MEN1 (0.35) CYP3A4CYP2C9CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108674-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-31 CN disclosed
CN-118084803-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
CN-118084802-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2024-05-28 CN disclosed
CN-111566094-B herbicidal compounds 先正达参股股份有限公司 2023-10-13 CN disclosed
CN-114555563-A Substituted pyridazinones as herbicides 先正达农作物保护股份公司 2022-05-27 CN disclosed
CN-111566094-A Herbicidal compounds 先正达参股股份有限公司 2020-08-21 CN disclosed