SCHEMBL22654098

SCHEMBL22654098

C=Cc1ccc(-c2cc(-c3ccc(C=C)cc3)c(N)c([N+](=O)[O-])c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 5/20 0.44
MAPT P10636 4/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
ERN1 O75460 3/20 0.36
HPRT1 P00492 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
CTSB P07858 1/20 0.35
DHFR P00374 1/20 0.34
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
HDAC2 Q92769 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
VCAM1 P19320 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20495264 0.80 TDP1 (0.47) TDP1MAPTMEN1POLBKMT2A
SCHEMBL28327664 0.77 VCAM1 (0.45) TDP1MAPTMEN1POLBKMT2A
SCHEMBL27975812 0.76 ALDH1A1 (0.56) TDP1MAPTMEN1POLBKMT2A
SCHEMBL22654094 0.76 ALDH1A1 (0.41) TDP1MEN1KMT2AALDH1A1TSHR
SCHEMBL20495060 0.75 TDP1 (0.46) TDP1MAPTMEN1POLBKMT2A
SCHEMBL14928263 0.74 AAK1 (0.48) TDP1MAPTMEN1POLBKMT2A
SCHEMBL8620067 0.73 ALDH1A1 (0.65) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL6226141 0.71 ERN1 (0.43) TDP1MAPTMEN1POLBKMT2A
SCHEMBL8838444 0.70 APP (0.53) MAPTPOLBALDH1A1
Styrene SCHEMBL27975454 0.70 ALDH1A1 (0.51) TDP1MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3737682-B1 C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES AND CURING PRODUCT OF CURABLE SILICON RESIN COMPOSITION AND C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES BASF SE (DE) 2025-12-17 EP disclosed
US-11987738-B2 C2-C3-alkenyl-substituted rylene imide dyes and curing product of curable silicon resin composition and C2-C3-alkenyl-substituted rylene imide dyes BASF SE (DE) 2024-05-21 US disclosed
CN-111699186-B C 2 -C 3 Alkenyl substituted ruimide dyes, curable silicone compositions and C 2 -C 3 Cured products of alkenyl substituted ruimide dyes 巴斯夫欧洲公司 2024-03-05 CN disclosed
US-20200362235-A1 C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES AND CURING PRODUCT OF CURABLE SILICON RESIN COMPOSITION AND C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES BASF SE (DE) 2020-11-19 US disclosed
EP-3737682-A2 C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES AND CURING PRODUCT OF CURABLE SILICON RESIN COMPOSITION AND C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES BASF SE (DE) 2020-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987738-B2 C2-C3-alkenyl-substituted rylene imide dyes and curing product of curable silicon resin composition and C2-C3-alkenyl-substituted rylene imide dyes RTN3, C9, RER1 TDP1 2510/4885MAPT 3902/4885MEN1 387/4885
US-20200362235-A1 C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES AND CURING PRODUCT OF CURABLE SILICON RESIN COMPOSITION AND C2-C3-ALKENYL-SUBSTITUTED RYLENE IMIDE DYES RTN3, C9, RER1 TDP1 2510/4885MAPT 3902/4885MEN1 387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.