Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9405380 | 0.97 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9405410 | 0.94 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9406843 | 0.92 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL38576 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TP53TSHRTDP1 | |
| SCHEMBL28312240 | 0.83 | CA12 (0.48) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL18918955 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TP53TSHRTDP1 | |
| SCHEMBL29168864 | 0.80 | CYP3A4 (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13970621 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Ethane SCHEMBL29138437 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL29201943 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041201-A | Preparation method of ioversol intermediate | 黑龙江迪诺医药有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116854610-A | Process for the preparation of impurities K and H of iopamidol and intermediates thereof | 江苏宇田医药有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116041201-A | Preparation method of ioversol intermediate | 黑龙江迪诺医药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| US-9328199-B2 | Cross-linked aramid | UNIVERSIDAD DE BURGOS (ES) | 2016-05-03 | — | — | US | disclosed |
| US-20150191570-A1 | CROSS-LINKED ARAMID | UNIVERSIDAD DE BURGOS (ES) | 2015-07-09 | — | — | US | disclosed |
| US-8962638-B2 | Piperidine inhibitors of janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| EP-2651917-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130266590-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2013-10-10 | — | — | US | disclosed |
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012080260-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
| US-5362905-A | Process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride | ZAMBON GROUP S.P.A. (IT) | 1994-11-08 | — | — | US | disclosed |
| EP-0610400-A1 | HYPERBRANCHED ARAMIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5321162-A | Benzenetriyl having halocarbonyl and N-sulfinylamino functional groups | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-5264543-A | Branched aromatic polyamides, processing aramid solutions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1993009162-A1 | HYPERBRANCHED ARAMIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| US-4283381-A | OPAQUING AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |
| EP-0022744-A2 | Tri-iodated bases, their preparation and X-ray contrast agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266590-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | KDM4E 3365/4885ALDH1A1 4312/4885MEN1 851/4885 |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | KDM4E 3741/4885ALDH1A1 4127/4885MEN1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.