Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9406843 | 0.97 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2265450 | 0.94 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9405380 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29168864 | 0.80 | CYP3A4 (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13970621 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28312240 | 0.79 | CA12 (0.48) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL38576 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TP53TSHRTDP1 | |
| SCHEMBL8196675 | 0.77 | PBRM1 (0.50) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL10567655 | 0.76 | NPC1 (0.56) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL10042217 | 0.76 | GLRA1 (0.37) | KDM4ETHRBSMN1; SMN2HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022406-A1 | MEMBRANE COMPRISING A SELECTIVELY PERMEABLE POLYMER LAYER OF A HIGHLY BRANCHED POLYMER | MERCK PATENT GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011074546-A1 | LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | 日産化学工業株式会社 (JP) | 2011-06-23 | — | — | WO | disclosed |
| EP-0610400-A1 | HYPERBRANCHED ARAMIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009162-A1 | HYPERBRANCHED ARAMIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |