SCHEMBL2265906

SCHEMBL2265906

ICc1ccc(C(c2ccc(CI)cc2)C(c2ccc(CI)cc2)c2ccc(CI)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
HIF1A Q16665 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649682 0.80 ALDH1A1 (0.37) TSHRTDP1ESR1ESR2IDO1
SCHEMBL5697082 0.73
SCHEMBL10001687 0.72 ESR1 (0.42) TSHRL3MBTL1ESR1ESR2
SCHEMBL5885407 0.71 ALDH1A1 (0.47) TSHRMAPK1TDP1ESR1ESR2
SCHEMBL16853360 0.71 GFER (0.47) L3MBTL1ESR1ESR2
SCHEMBL8216377 0.71 ESR1 (0.36) ESR1ESR2IDO1
SCHEMBL284077 0.69
SCHEMBL7627595 0.68 PTGS2 (0.67) TSHRESR1
SCHEMBL13683339 0.68 EPHX1 (0.42) TDP1PGK1PGK2ESR1
SCHEMBL16716676 0.67 PTGS1 (0.47) TSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8710151-B2 Onium salt-containing polymer NIPPON SODA CO., LTD. (JP) 2014-04-29 US disclosed
US-20110201759-A1 ONIUM SALT-CONTAINING POLYMER NIPPON SODA CO., LTD. (JP) 2011-08-18 US disclosed
EP-2226343-A1 ONIUM SALT-CONTAINING POLYMER Nippon Soda Co., Ltd. (JP) 2010-09-08 EP disclosed