Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 15/20 | 0.42 |
| ▸ | THRA | P10827 | 14/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22660382 | 0.89 | THRB (0.44) | THRBTHRA | |
| SCHEMBL28500041 | 0.81 | THRB (0.49) | THRBTHRA | |
| SCHEMBL30399811 | 0.78 | THRB (0.52) | THRBTHRA | |
| SCHEMBL22660350 | 0.78 | THRB (0.52) | THRBTHRA | |
| SCHEMBL22660329 | 0.77 | THRB (0.44) | THRBTHRA | |
| SCHEMBL2921895 | 0.76 | THRA (0.67) | THRBTHRA | |
| SCHEMBL30399816 | 0.76 | LMNA (0.47) | THRBTHRA | |
| SCHEMBL22660344 | 0.76 | LMNA (0.47) | THRBTHRA | |
| SCHEMBL13116495 | 0.76 | THRB (0.68) | THRBTHRA | |
| SCHEMBL22668330 | 0.75 | THRB (0.51) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228577-A1 | PYRIDAZINONE DERIVATIVE AND USE THEREOF | 深圳微芯生物科技股份有限公司 | 2020-11-19 | — | — | WO | disclosed |