SCHEMBL22665491

SCHEMBL22665491

c1ccc(-n2c3ccccc3c3cc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)ccc32)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.60
KDM4E B2RXH2 3/20 0.60
ATM Q13315 1/20 0.60
PTPN1 P18031 1/20 0.36
ALDH1A1 P00352 3/20 0.36
TSHR P16473 2/20 0.36
KMT2A Q03164 3/20 0.36
MAPK8 P45983 2/20 0.36
IL1R1 P14778 1/20 0.36
MAPK1 P28482 3/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PGR P06401 1/20 0.35
HTT P42858 2/20 0.35
MAPK9 P45984 1/20 0.35
MAPT P10636 1/20 0.35
KDR P35968 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19044681 1.00 L3MBTL1 (0.60) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL18381748 0.98 L3MBTL1 (0.58) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL17463232 0.98 L3MBTL1 (0.58) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL12879552 0.97 KDM4E (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL24398161 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL10144912 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL12105021 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL17463238 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL26717852 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1
SCHEMBL26717866 0.95 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230189633-A1 POLYCYCLIC COMPOUND, LIGHT EMITTING ELEMENT INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
US-20230189633-A1 POLYCYCLIC COMPOUND, LIGHT EMITTING ELEMENT INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-15 US disclosed
EP-3739645-A2 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2020-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230189633-A1 POLYCYCLIC COMPOUND, LIGHT EMITTING ELEMENT INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME USE1, EMC1, TMEM109 L3MBTL1 2775/4885KDM4E 3570/4885ATM 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.