SCHEMBL22668246

SCHEMBL22668246

CCC(C)(C)OP(=O)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.47
SRC P12931 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTT P42858 1/20 0.39
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ANPEP P15144 1/20 0.37
LAP3 P28838 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28059855 0.96 L3MBTL1 (0.47) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL29090042 0.87 L3MBTL1 (0.49) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL464914 0.81 SRC (0.48) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL28278294 0.80 SRC (0.44) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL1072680 0.77 SRC (0.48) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL9874206 0.76 MAPK1 (0.47) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL31480676 0.76 TSHR (0.49) SRCALDH1A1MEN1KMT2ATSHR
SCHEMBL17544935 0.76 ALDH1A1 (0.46) L3MBTL1SRCTDP1ALDH1A1MEN1
SCHEMBL13538051 0.76 L3MBTL1 (0.52) L3MBTL1SRCTDP1ALDH1A1MEN1
Triphenyl Phosphate SCHEMBL28231928 0.75 SRC (0.56) L3MBTL1SRCTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106604981-B Lubricant compositions for improved thermo-oxidative stability and color stability SK新技术株式会社 2020-02-07 CN claimed
US-11370775-B2 Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors Tseng, Yufeng Jane (US) 2022-06-28 US disclosed
US-20200361894-A1 NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) 2020-11-19 US disclosed
CN-106604981-B Lubricant compositions for improved thermo-oxidative stability and color stability SK新技术株式会社 2020-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370775-B2 Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors DAO, DDO, IL4I1 L3MBTL1 1732/4885SRC 3981/4885TDP1 1108/4885
US-20200361894-A1 NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS D-AMINO ACID OXIDASE (DAAO) INHIBITORS DAO, DDO, DDC L3MBTL1 877/4885SRC 3521/4885TDP1 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.