Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 7/20 | 1.00 |
| ▸ | SLC1A3 | P43003 | 6/20 | 1.00 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.74 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.70 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.61 |
| ▸ | GRIK2 | Q13002 | 8/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL175940 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| Leucine SCHEMBL8568060 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| Leucine SCHEMBL2478164 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| Leucine SCHEMBL8568063 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| Leucine SCHEMBL3888 | 0.85 | — | — | |
| Leucine SCHEMBL25241602 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| D-Leucine SCHEMBL42012 | 0.85 | — | — | |
| Leucine SCHEMBL331557 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 | |
| Leucine SCHEMBL20362356 | 0.85 | — | — | |
| D-Leucine SCHEMBL9100148 | 0.85 | SLC7A5 (1.00) | SLC1A2SLC1A3SLC7A5SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445440-B2 | Dimeric IAP inhibitors | NOVARTIS AG (CH) | 2013-05-21 | — | — | US | disclosed |
| EP-2539333-A1 | DIMERIC IAP INHIBITORS | Novartis AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104266-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206690-A1 | DIMERIC IAP INHIBITORS | XIAP, BIRC5, BIRC2 | SLC1A2 4283/4885SLC1A3 4126/4885SLC7A5 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.