Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453030 | 0.86 | EPHX2 (0.54) | ALDH1A1KMT2ATSHRHRH3LMNA | |
| SCHEMBL19773151 | 0.86 | EPHX2 (0.54) | ALDH1A1KMT2ATSHRHRH3LMNA | |
| SCHEMBL24204794 | 0.85 | GNAI3 (0.51) | ALDH1A1KMT2ATSHRHRH3POLB | |
| SCHEMBL14614943 | 0.84 | MEN1 (0.59) | ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL14035661 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KMT2ATSHRHRH3LMNA | |
| SCHEMBL11490502 | 0.83 | GNAI3 (0.51) | ALDH1A1KMT2ATSHRHRH3KDM4E | |
| SCHEMBL24206641 | 0.83 | ACACB (0.43) | ALDH1A1KMT2ATSHRHRH3MEN1 | |
| SCHEMBL24204480 | 0.83 | GNAI3 (0.51) | ALDH1A1KMT2ATSHRHRH3LMNA | |
| SCHEMBL3766758 | 0.81 | CHRNB2 (0.47) | ALDH1A1KMT2AHRH3LMNAKDM4E | |
| SCHEMBL22672734 | 0.80 | HRH3 (0.51) | ALDH1A1KMT2ATSHRHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153209-A1 | METHOD FOR TREATING LYSOSOMAL STORAGE DISEASES WITH HISTATIN PEPTIDES | The Board of Trustees of the University of Illinois (US) | 2023-03-29 | — | — | EP | disclosed |
| WO-2007109615-A2 | β -LACTAMYL VASOPRESSIN V2 ANTAGONISTS | AZEVAN PHARMACEUTICALS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |