SCHEMBL2267737

SCHEMBL2267737

CN[SiH](C=CC(C)C)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.31
SLC18A2 Q05940 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275037 0.80 SIGMAR1 (0.33) SIGMAR1TDP1
SCHEMBL2268089 0.72
SCHEMBL2270393 0.71 TSHR (0.33)
SCHEMBL2269157 0.69
SCHEMBL2276415 0.66 PGR (0.31)
SCHEMBL2270888 0.64 TDP1 (0.36) TAAR1SLC18A2SIGMAR1TDP1
SCHEMBL2103203 0.62
SCHEMBL2101602 0.62 TSHR (0.41) TAAR1SLC18A2SIGMAR1TDP1
SCHEMBL2268375 0.62 TSHR (0.41) TAAR1SLC18A2SIGMAR1TDP1
SCHEMBL2270141 0.60 TSHR (0.39) TAAR1SLC18A2SIGMAR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed