Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25C | P30307 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680472 | 0.88 | EYA3 (0.77) | EYA3SLC22A12TTRAKR1B1ESR1 | |
| Poztinurad SCHEMBL15698085 | 0.75 | EYA3 (1.00) | EYA3SLC22A12TTRESR1CYP2C19 | |
| Poztinurad SCHEMBL29569243 | 0.75 | EYA3 (1.00) | EYA3SLC22A12TTRESR1CYP2C19 | |
| SCHEMBL25814853 | 0.74 | SLC22A12 (0.58) | EYA3SLC22A12TTRESR1ESR2 | |
| SCHEMBL25814802 | 0.72 | EYA3 (0.81) | EYA3SLC22A12TTRESR1CYP2C19 | |
| SCHEMBL25815062 | 0.72 | EYA3 (0.56) | EYA3SLC22A12TTRCA2CYP2C19 | |
| SCHEMBL20702027 | 0.70 | EYA3 (0.72) | EYA3SLC22A12TTRESR1CYP2C19 | |
| Pozdeutinurad SCHEMBL22032803 | 0.69 | EYA3 (0.68) | EYA3SLC22A12TTRESR1CYP2C19 | |
| Pozdeutinurad SCHEMBL30421663 | 0.68 | EYA3 (0.67) | EYA3SLC22A12TTRESR1CYP2C19 | |
| SCHEMBL29748630 | 0.68 | ALDH1A1 (0.53) | SLC22A12TTRESR1ESR2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020232156-A1 | COMPOUND FOR TREATING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-11-19 | — | — | WO | disclosed |