Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB7A | P51149 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 7/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 7/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680878 | 0.83 | RAB7A (0.48) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21247496 | 0.82 | RAB7A (0.57) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL22680875 | 0.78 | RAB7A (0.48) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL22680796 | 0.73 | NOD1 (0.40) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21260980 | 0.73 | RAB7A (0.58) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21247292 | 0.73 | RAB7A (0.54) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21259035 | 0.73 | MAPT (0.49) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21247382 | 0.72 | RAB7A (0.80) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21247258 | 0.71 | RAB7A (0.57) | RAB7AFABP4FABP5KIF11MAPT | |
| SCHEMBL21261032 | 0.70 | RAB7A (0.60) | RAB7AFABP4FABP5KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | RAB7A 2283/4885FABP4 331/4885FABP5 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.