Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 3/20 | 0.34 |
| ▸ | CHUK | O15111 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11354415 | 0.98 | SLC6A2 (0.36) | SLC6A2HTTDPP4ADORA1ADORA2A | |
| SCHEMBL2271059 | 0.81 | PDE4D (0.42) | HTTDPP4KDM4EHSP90AA1FGFR1 | |
| SCHEMBL2268088 | 0.75 | ADORA2A (0.42) | ADORA1ADORA2ACDK2ADORA2BPDE4A | |
| SCHEMBL2268073 | 0.74 | ADORA2A (0.40) | SLC6A2HTTADORA1ADORA2ACDK2 | |
| SCHEMBL2270147 | 0.72 | ADORA2A (0.45) | ADORA2AKDM4ELMNAPOLBPDE4A | |
| SCHEMBL3185680 | 0.71 | DDB1 (0.41) | DPP4ADORA1KDM4EFGFR1SRC | |
| SCHEMBL8050564 | 0.71 | FGFR1 (0.56) | DPP4KDM4EFGFR1MAPTIDO1 | |
| SCHEMBL31103863 | 0.67 | LMNA (0.40) | KDM4EHSP90AA1BRD4LMNAMAPT | |
| SCHEMBL13439510 | 0.67 | KDM4E (0.44) | SLC6A2HTTKDM4EL3MBTL1BRD4 | |
| SCHEMBL8737256 | 0.67 | IKBKB (0.36) | DPP4ADORA1ADORA2AIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002520-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2008-10-29 | — | — | EP | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-6893470-B1 | Keratinous fibre oxidation dyeing composition containing a laccase and dyeing method using same | L'OREAL S.A. (FR) | 2005-05-17 | — | — | US | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| EP-0988021-B1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | OREAL (FR) | 2003-11-12 | — | — | EP | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| US-6395042-B1 | OXIDATION BASE, HETEROCYCLIC COUPLERS FOR OXIDATION COLOR DYE | L'ORÉAL (FR) | 2002-05-28 | — | — | US | claimed |
| EP-1181005-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | claimed |
| WO-2001066071-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | claimed |
| EP-0988021-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 2000-03-29 | — | — | EP | claimed |
| WO-1998055083-A1 | KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-12-10 | — | — | WO | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| US-5769903-A | Composition for the oxidation dyeing of keratin fibers, comprising an oxidation base, an indole coupler and an additional heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-06-23 | — | — | US | claimed |
| EP-0728464-B1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| EP-0605320-B1 | Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5578087-A | Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them | L'OREAL (FR) | 1996-11-26 | — | — | US | claimed |
| EP-0728466-A1 | Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0728464-A1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0605320-A1 | Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same | L'OREAL (FR) | 1994-07-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | SLC6A2 2536/4885HTT 991/4885DPP4 3622/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | SLC6A2 3304/4885HTT 586/4885DPP4 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.