SCHEMBL2268370

SCHEMBL2268370

CC(C)(C)OC(=O)Oc1ccc(C2(C(=O)OC(C)(C)C)C=CC=CC2N)cc1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.46
KDM1A O60341 1/20 0.39
CA2 P00918 1/20 0.36
MAPKAPK2 P49137 2/20 0.32
CTSD P07339 1/20 0.30
CTSE P14091 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276486 0.83 RORC (0.33) KDM1A
SCHEMBL4091330 0.74 SLC6A4 (0.38)
SCHEMBL4061370 0.72 ELANE (0.81) ELANEKDM1ACA2MAPKAPK2
SCHEMBL2366870 0.67 ELANE (0.68) ELANEKDM1ACA2MAPKAPK2
SCHEMBL7195551 0.67 ELANE (0.68) ELANEKDM1ACA2MAPKAPK2
SCHEMBL4059798 0.67 ELANE (0.72) ELANEKDM1ACA2MAPKAPK2
SCHEMBL30080569 0.66 ELANE (0.66) ELANEKDM1ACA2MAPKAPK2
SCHEMBL12228673 0.66 ELANE (0.66) ELANEKDM1ACA2MAPKAPK2
SCHEMBL4057059 0.66 ELANE (0.70) ELANEKDM1ACA2
SCHEMBL7195555 0.66 ELANE (0.70) ELANEKDM1ACA2MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 ELANE 427/4885KDM1A 443/4885CA2 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.