Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685245 | 0.92 | MAP4K4 (0.41) | IDO1CYP2C9MAP4K4MINK1TNIK | |
| SCHEMBL22685074 | 0.89 | IDO1 (0.51) | IDO1CYP2C9WDR91MAP4K4PDE2A | |
| SCHEMBL22685078 | 0.88 | WDR91 (0.53) | IDO1CYP2C9WDR91MAP4K4PDE2A | |
| SCHEMBL22685072 | 0.88 | IDO1 (0.43) | IDO1CYP2C9WDR91PDE2AHDAC6 | |
| SCHEMBL22685075 | 0.86 | IDO1 (0.43) | IDO1CYP2C9WDR91MAP4K4PDE2A | |
| SCHEMBL22438817 | 0.81 | EGLN1 (0.41) | IDO1CYP2C9MAP4K4MINK1TNIK | |
| SCHEMBL22438754 | 0.80 | FASN (0.43) | IDO1CYP2C9MAP4K4MINK1TNIK | |
| SCHEMBL30070801 | 0.80 | FASN (0.43) | IDO1CYP2C9MAP4K4MINK1TNIK | |
| SCHEMBL23908259 | 0.80 | IDO1 (0.45) | IDO1CYP2C9MAP4K4MINK1TNIK | |
| SCHEMBL22438887 | 0.79 | CYP2C9 (0.53) | IDO1CYP2C9MAP4K4MINK1TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |