Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685073 | 0.92 | IDO1 (0.41) | MAP4K4MINK1TNIKEGLN1KDM1A | |
| SCHEMBL22438817 | 0.87 | EGLN1 (0.41) | MAP4K4MINK1TNIKEGLN1CXCR3 | |
| SCHEMBL22438754 | 0.86 | FASN (0.43) | MAP4K4MINK1TNIKEGLN1CXCR3 | |
| SCHEMBL30070801 | 0.86 | FASN (0.43) | MAP4K4MINK1TNIKEGLN1CXCR3 | |
| SCHEMBL23908259 | 0.85 | IDO1 (0.45) | MAP4K4MINK1TNIKEGLN1CYP2C9 | |
| SCHEMBL22685247 | 0.85 | ROCK2 (0.41) | MAP4K4DEGS1CYP2C9IDO1PDE2A | |
| SCHEMBL22438887 | 0.85 | CYP2C9 (0.53) | MAP4K4MINK1TNIKEGLN1CXCR3 | |
| SCHEMBL22685250 | 0.83 | PTPN1 (0.40) | EGLN1CYP2C9IDO1PDE2A | |
| SCHEMBL22438916 | 0.83 | ROCK2 (0.47) | MAP4K4MINK1TNIKEGLN1CYP2C9 | |
| SCHEMBL22685330 | 0.83 | CXCR3 (0.42) | MAP4K4MINK1TNIKEGLN1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |