Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 11/20 | 0.53 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685074 | 0.92 | IDO1 (0.51) | WDR91IDO1CYP2C9PDE2AMAP4K4 | |
| SCHEMBL22685072 | 0.91 | IDO1 (0.43) | WDR91IDO1CYP2C9PDE2A | |
| SCHEMBL22685075 | 0.88 | IDO1 (0.43) | WDR91IDO1CYP2C9PDE2AMAP4K4 | |
| SCHEMBL22685073 | 0.88 | IDO1 (0.41) | WDR91IDO1CYP2C9PDE2AMAP4K4 | |
| SCHEMBL22685351 | 0.83 | WDR91 (0.54) | WDR91IDO1PDE2AMAP4K4 | |
| SCHEMBL22685177 | 0.83 | IDO1 (0.42) | WDR91IDO1F10MALT1MAP4K4 | |
| SCHEMBL22684760 | 0.81 | WDR91 (0.53) | WDR91PDE2AMALT1 | |
| SCHEMBL22685262 | 0.80 | WDR91 (0.40) | WDR91PDE2AF10MALT1MAP4K4 | |
| SCHEMBL22439026 | 0.80 | IDO1 (0.66) | WDR91IDO1CYP2C9PDE2A | |
| SCHEMBL22685247 | 0.80 | ROCK2 (0.41) | IDO1CYP2C9PDE2AF10MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |