Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | WDR91 | A4D1P6 | 7/20 | 0.42 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685074 | 0.92 | IDO1 (0.51) | IDO1CYP2C9WDR91PDE2AABL1 | |
| SCHEMBL22685078 | 0.91 | WDR91 (0.53) | IDO1CYP2C9WDR91PDE2A | |
| SCHEMBL22685075 | 0.88 | IDO1 (0.43) | IDO1CYP2C9WDR91PDE2AABL1 | |
| SCHEMBL22685073 | 0.88 | IDO1 (0.41) | IDO1CYP2C9WDR91PDE2AHDAC6 | |
| SCHEMBL22685245 | 0.80 | MAP4K4 (0.41) | IDO1CYP2C9PDE2A | |
| SCHEMBL22685247 | 0.80 | ROCK2 (0.41) | IDO1CYP2C9PDE2AHDAC3HDAC1 | |
| SCHEMBL22439026 | 0.80 | IDO1 (0.66) | IDO1CYP2C9WDR91PDE2A | |
| SCHEMBL22685250 | 0.78 | PTPN1 (0.40) | IDO1CYP2C9PDE2AABL1KCNH2 | |
| SCHEMBL22684758 | 0.77 | WDR91 (0.43) | WDR91PDE2ABACE1HDAC3HDAC1 | |
| SCHEMBL22685165 | 0.77 | WDR91 (0.42) | WDR91PDE2AABL1BACE1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |