Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 11/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685351 | 0.89 | WDR91 (0.54) | IDO1PDE2AWDR91CXCR3MAP4K4 | |
| SCHEMBL22684799 | 0.87 | IDO1 (0.39) | IDO1PDE2A | |
| SCHEMBL22685330 | 0.83 | CXCR3 (0.42) | PDE2ACXCR3MAP4K4 | |
| SCHEMBL22685324 | 0.82 | WDR91 (0.40) | IDO1PDE2AWDR91CXCR3PTGER4 | |
| SCHEMBL22686791 | 0.81 | WDR91 (0.44) | IDO1WDR91CXCR3HSD11B1MAP4K4 | |
| SCHEMBL22686805 | 0.80 | PTGER4 (0.42) | IDO1PDE2AWDR91CXCR3PTGER4 | |
| SCHEMBL22685191 | 0.80 | WDR91 (0.43) | IDO1PDE2AWDR91 | |
| SCHEMBL22685193 | 0.80 | PDE2A (0.38) | IDO1PDE2APTGER4PTGDR | |
| SCHEMBL22685248 | 0.79 | PTPN1 (0.39) | PDE2A | |
| SCHEMBL22685076 | 0.78 | PTGER4 (0.46) | PDE2AWDR91CXCR3PTGER4PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |