Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 12/20 | 0.54 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685191 | 0.91 | WDR91 (0.43) | WDR91PDE2AIDO1 | |
| SCHEMBL22685173 | 0.89 | IDO1 (0.42) | WDR91PDE2ACXCR3IDO1MAP4K4 | |
| SCHEMBL22684822 | 0.88 | WDR91 (0.40) | WDR91PDE2AIDO1KDM4EALDH1A1 | |
| SCHEMBL22685244 | 0.84 | WDR91 (0.40) | WDR91PDE2AIDO1 | |
| SCHEMBL22685078 | 0.83 | WDR91 (0.53) | WDR91PDE2AIDO1MAP4K4 | |
| SCHEMBL22684799 | 0.82 | IDO1 (0.39) | PDE2AIDO1 | |
| SCHEMBL22685330 | 0.79 | CXCR3 (0.42) | PDE2ACXCR3MAP4K4 | |
| SCHEMBL22685198 | 0.78 | WDR91 (0.53) | WDR91KDM4EMAP4K4 | |
| SCHEMBL22685311 | 0.77 | WDR91 (0.55) | WDR91MAP4K4 | |
| SCHEMBL22685324 | 0.77 | WDR91 (0.40) | WDR91PDE2ACXCR3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |