Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685244 | 0.92 | WDR91 (0.40) | PTPN1NNMTMKNK1MKNK2KCNH2 | |
| SCHEMBL22685250 | 0.86 | PTPN1 (0.40) | PTPN1ROCK2ROCK1NNMTMKNK1 | |
| SCHEMBL22684799 | 0.84 | IDO1 (0.39) | KCNH2HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685330 | 0.80 | CXCR3 (0.42) | EGLN1PDE2A | |
| SCHEMBL22685173 | 0.79 | IDO1 (0.42) | PDE2A | |
| SCHEMBL22686783 | 0.79 | WDR91 (0.42) | ROCK2ROCK1BTKKCNH2HDAC3 | |
| SCHEMBL22685247 | 0.77 | ROCK2 (0.41) | PTPN1ROCK2ROCK1HDAC3HDAC1 | |
| SCHEMBL22685327 | 0.76 | PDE2A (0.39) | PDE2A | |
| SCHEMBL22685191 | 0.76 | WDR91 (0.43) | KCNH2PDE2A | |
| SCHEMBL22685351 | 0.75 | WDR91 (0.54) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |