Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22438850 | 0.87 | EGLN1 (0.44) | EGLN1CXCR3MAP4K4 | |
| SCHEMBL22685060 | 0.83 | WDR91 (0.45) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685238 | 0.77 | HDAC3 (0.47) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22438857 | 0.76 | EGLN1 (0.45) | EGLN1MAP4K4 | |
| SCHEMBL23908259 | 0.75 | IDO1 (0.45) | EGLN1MAP4K4 | |
| SCHEMBL22438744 | 0.75 | IDO1 (0.45) | EGLN1MAP4K4 | |
| SCHEMBL22685249 | 0.74 | WDR91 (0.41) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22686788 | 0.74 | HDAC3 (0.46) | WDR91HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684820 | 0.73 | DEGS1 (0.45) | HDAC3HDAC1HDAC2HDAC6EGLN1 | |
| SCHEMBL22685209 | 0.72 | EGLN2 (0.41) | MAP4K1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |