Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | WDR91 | A4D1P6 | 5/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686788 | 0.89 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22685198 | 0.81 | WDR91 (0.53) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22685236 | 0.78 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6BTK | |
| SCHEMBL22685202 | 0.77 | WDR91 (0.40) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22686789 | 0.77 | WDR91 (0.43) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22686791 | 0.77 | WDR91 (0.44) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22685253 | 0.76 | PDE2A (0.42) | HDAC3HDAC1HDAC2HDAC6BTK | |
| SCHEMBL22685237 | 0.75 | BTK (0.41) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22685249 | 0.75 | WDR91 (0.41) | HDAC3HDAC1HDAC2HDAC6WDR91 | |
| SCHEMBL22438959 | 0.70 | WDR91 (0.57) | HDAC3HDAC1HDAC2HDAC6WDR91 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |