Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685329 | 0.90 | IDO1 (0.43) | MAP4K4ROCK2ROCK1HDAC3HDAC1 | |
| SCHEMBL22685322 | 0.88 | ROCK2 (0.38) | MAP4K4ROCK2ROCK1OPRD1KCNH2 | |
| SCHEMBL22685262 | 0.88 | WDR91 (0.40) | WDR91MAP4K4HDAC3HDAC1HDAC2 | |
| SCHEMBL22686789 | 0.82 | WDR91 (0.43) | WDR91MAP4K4ROCK2ROCK1HDAC3 | |
| SCHEMBL22685264 | 0.82 | PDE2A (0.42) | MAP4K4ROCK2ROCK1HDAC3HDAC1 | |
| SCHEMBL22686783 | 0.82 | WDR91 (0.42) | WDR91MAP4K4ROCK2ROCK1HDAC3 | |
| SCHEMBL22685250 | 0.82 | PTPN1 (0.40) | ROCK2ROCK1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685183 | 0.80 | MALT1 (0.44) | WDR91ROCK2ROCK1HDAC3HDAC1 | |
| SCHEMBL22685247 | 0.80 | ROCK2 (0.41) | MAP4K4ROCK2ROCK1HDAC3HDAC1 | |
| SCHEMBL22685246 | 0.77 | WDR91 (0.45) | WDR91MAP4K4HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |